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The inhibition of VMAT-2, encoded by Slc18a2, results in reduced vesicular storage and depletion of monoamines, and produces the same pattern of preference for low-effort option, without interfering with the devaluation test (which indicates integrity of outcome valuation) (Salamone et al., 2016a)

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14 In addition to acting as neuronal and mitochondrial toxins, some pesticides also impair the breakdown of protein aggregates, like Lewy bodies